Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.74 |
| ▸ | CA1 | P00915 | 6/20 | 0.74 |
| ▸ | CA2 | P00918 | 6/20 | 0.74 |
| ▸ | CA6 | P23280 | 6/20 | 0.74 |
| ▸ | CA7 | P43166 | 6/20 | 0.74 |
| ▸ | CA9 | Q16790 | 6/20 | 0.74 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.74 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.74 |
| ▸ | CA5A | P35218 | 5/20 | 0.74 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | HTR1A | P08908 | 1/20 | 0.74 |
| ▸ | CA4 | P22748 | 1/20 | 0.74 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.74 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.74 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.74 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.74 |
| ▸ | APP | P05067 | 9/20 | 0.62 |
| ▸ | AQP1 | P29972 | 1/20 | 0.54 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204408 | 0.87 | CA12 (0.78) | CA12CA1CA2CA6CA7 | |
| Furosemide SCHEMBL9811 | 0.86 | CISD1 (1.00) | CA12CA1CA2CA6CA7 | |
| Furosemide SCHEMBL428921 | 0.86 | CISD1 (1.00) | CA12CA1CA2CA6CA7 | |
| Furosemide SCHEMBL29406913 | 0.86 | CISD1 (1.00) | CA12CA1CA2CA6CA7 | |
| Furosemide SCHEMBL5483691 | 0.85 | CISD1 (0.94) | CA12CA1CA2CA6CA7 | |
| SCHEMBL230328 | 0.85 | CA12 (0.72) | CA12CA1CA2CA6CA7 | |
| SCHEMBL230993 | 0.85 | CA12 (0.72) | CA12CA1CA2CA6CA7 | |
| SCHEMBL230327 | 0.85 | CA12 (0.72) | CA12CA1CA2CA6CA7 | |
| Furosemide SCHEMBL2953945 | 0.85 | CISD1 (0.98) | CA12CA1CA2CA6CA7 | |
| Furosemide SCHEMBL11898462 | 0.85 | CISD1 (0.98) | CA12CA1CA2CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1682709-A | Furosemide oral disintegration tablet and its preparing method | LUYE NATURAL MEDICINE R & D CO (CN) | 2005-10-19 | — | — | CN | disclosed |