Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610896 | 0.82 | CNR2 (0.38) | NFE2L2MAOBMAOALCKHDAC4 | |
| SCHEMBL610897 | 0.82 | CNR2 (0.38) | NFE2L2MAOBMAOALCKHDAC4 | |
| SCHEMBL27492384 | 0.81 | KDM4E (0.59) | HDAC4MEF2DKDM4EALDH1A1PKM | |
| SCHEMBL28753500 | 0.80 | MAOB (0.50) | NFE2L2MAOBCYP19A1MAOALCK | |
| SCHEMBL9454709 | 0.79 | ALDH1A1 (0.52) | NFE2L2MAOBCYP19A1MAOALCK | |
| SCHEMBL9335390 | 0.79 | TSHR (0.52) | NFE2L2MAOBCYP19A1MAOALCK | |
| SCHEMBL16105668 | 0.79 | TP53 (0.52) | NFE2L2MAOBCYP19A1MAOALCK | |
| SCHEMBL8622975 | 0.79 | ALDH1A1 (0.52) | NFE2L2MAOBCYP19A1MAOALCK | |
| SCHEMBL9335412 | 0.79 | TSHR (0.52) | NFE2L2MAOBCYP19A1MAOALCK | |
| SCHEMBL9454625 | 0.79 | TSHR (0.52) | NFE2L2MAOBCYP19A1MAOALCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |