Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622972 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TRPA1TSHRNFE2L2MAOB | |
| SCHEMBL9454709 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TRPA1TSHRNFE2L2MAOB | |
| SCHEMBL26316674 | 0.85 | NFE2L2 (0.56) | ALDH1A1NFE2L2CYP19A1LCKRELA | |
| SCHEMBL7489498 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TRPA1TSHRNFE2L2LCK | |
| SCHEMBL27450402 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TRPA1TSHRNFE2L2MAOB | |
| SCHEMBL18197883 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TRPA1TSHRNFE2L2LCK | |
| SCHEMBL7489493 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TRPA1TSHRNFE2L2LCK | |
| SCHEMBL3565889 | 0.81 | KDM4E (0.59) | ALDH1A1TSHRHDAC4MEF2DKDM4E | |
| SCHEMBL3565886 | 0.81 | KDM4E (0.59) | ALDH1A1TSHRHDAC4MEF2DKDM4E | |
| SCHEMBL9455094 | 0.81 | RAB9A (0.45) | ALDH1A1TRPA1TSHRNFE2L2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719303-A | USEFUL FOR MEDICALLY TREATING HYPERLIPEMIA | EISAI CO., LTD. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0688325-A1 | PHOSPHONIC ACID DERIVATIVES | Eisai Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| WO-1994020508-A1 | PHOSPHONIC ACID DERIVATIVES | EISAI CO., LTD. (JP) | 1994-09-15 | — | — | WO | disclosed |
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0007576-B1 | ESTERS OF STILBENE DERIVATIVES, PROCESS FOR THEIR PREPARATION, STILBENE-ALCOHOLS AS INTERMEDIATE PRODUCTS, USE OF THE ESTERS AS INSECTICIDES | BAYER AG (DE) | 1983-11-16 | — | — | EP | disclosed |
| US-4271186-A | Stilbene compounds and insecticidal/acaricidal compositions | BAYER AKTIENGESELLSCHAFT (DE) | 1981-06-02 | — | — | US | disclosed |
| EP-0007576-A2 | Esters of stilbene derivatives, process for their preparation, stilbene-alcohols as intermediate products, use of the esters as insecticides | BAYER AG (DE) | 1980-02-06 | — | — | EP | disclosed |