Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27338617 | 0.92 | TSHR (0.41) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL8351572 | 0.92 | TSHR (0.41) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL6002127 | 0.92 | TSHR (0.41) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL6003116 | 0.90 | LTA4H (0.41) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL6002413 | 0.85 | LTA4H (0.41) | NPC1JAK2RAB9APAX8BCHE | |
| SCHEMBL21051141 | 0.77 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL11638360 | 0.73 | NPC1 (0.45) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL27610392 | 0.73 | KDM4E (0.30) | BCHEACHE | |
| SCHEMBL16415141 | 0.73 | NPC1 (0.51) | NPC1JAK2RAB9APAX8 | |
| SCHEMBL7651322 | 0.73 | NPC1 (0.51) | NPC1JAK2RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |