SCHEMBL7651322

SCHEMBL7651322

CCCCCCCCCCCCN(C=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.51
JAK2 O60674 1/20 0.51
RAB9A P51151 1/20 0.51
PAX8 Q06710 1/20 0.51
KCNH2 Q12809 6/20 0.45
TACR1 P25103 1/20 0.43
TDP1 Q9NUW8 2/20 0.42
ICMT O60725 1/20 0.42
ALB P02768 1/20 0.42
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
LMNA P02545 1/20 0.40
CNR2 P34972 2/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16415141 1.00 NPC1 (0.51) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL16415177 1.00 NPC1 (0.51) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL3458582 1.00 NPC1 (0.51) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL1685969 1.00 NPC1 (0.51) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL707050 1.00 NPC1 (0.51) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL16414653 1.00 NPC1 (0.51) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL704307 0.98 NPC1 (0.49) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL489809 0.92 TDP1 (0.46) NPC1JAK2RAB9APAX8KCNH2
Chloromethane SCHEMBL7281088 0.89 NPC1 (0.44) NPC1JAK2RAB9APAX8KCNH2
SCHEMBL709444 0.84 TP53 (0.44) NPC1JAK2RAB9APAX8TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337176-B1 COLOR REPRODUCTION AND SHARPNESS; RAPID PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 2002-01-08 US claimed
EP-2841433-B1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL CO (JP) 2017-06-21 EP disclosed
US-9380782-B2 Tetrazolinone compounds and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-05 US disclosed
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-01-29 US disclosed
WO-2013162077-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
US-6337176-B1 COLOR REPRODUCTION AND SHARPNESS; RAPID PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 2002-01-08 US disclosed
US-5728514-A Silver halide color photographic material and method for forming color image FUJI PHOTO FILM CO, LTD. (JP) 1998-03-17 US disclosed
EP-0317983-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-01 EP disclosed
US-5100771-A SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL WITH WATER INSOLUBLE ORGANIC SOLVENT SOLUBLE POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1992-03-31 US disclosed
EP-0317983-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150031733-A1 TETRAZOLINONE COMPOUNDS AND ITS USE CBR3, CYP51A1, CYP8B1 NPC1 2859/4885JAK2 1162/4885RAB9A 515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.