Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LCAT | P04180 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5631489 | 1.00 | DRD2 (0.46) | DRD2DRD3NOTUMRAD52ALOX5 | |
| Trifluoroacetic Acid SCHEMBL3847590 | 0.80 | DRD2 (0.74) | DRD2DRD3NOTUMLCATHTR2C | |
| Trifluoroacetic Acid SCHEMBL5632214 | 0.79 | RAD52 (0.44) | RAD52HTR2CHTR2ADPP4DPP9 | |
| SCHEMBL6839730 | 0.79 | DRD2 (0.52) | DRD2DRD3NOTUMALOX5HTR2C | |
| Trifluoroacetic Acid SCHEMBL5633122 | 0.77 | PKM (0.40) | RAD52HTR2CHTR2AHTR2BDPP4 | |
| Trifluoroacetic Acid SCHEMBL5631915 | 0.77 | PKM (0.40) | RAD52HTR2CHTR2AHTR2BDPP4 | |
| Trifluoroacetic Acid SCHEMBL5471477 | 0.77 | DPP4 (0.46) | LCATHTR2CHTR2ACHRM2CHRM1 | |
| SCHEMBL5632538 | 0.74 | HTR2C (0.58) | RAD52ALOX5HTR2CHTR2AHTR2B | |
| SCHEMBL5631654 | 0.74 | HTR2C (0.58) | RAD52ALOX5HTR2CHTR2AHTR2B | |
| SCHEMBL5632981 | 0.74 | HTR2C (0.58) | RAD52ALOX5HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809545-A | N-phenyl-piperazine derivatives and methods of prophylaxis or treatment of 5HT2c | ARENA PHARM INC (US) | 2006-07-26 | — | — | CN | disclosed |