Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 7/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 7/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484077 | 0.88 | CSF1R (0.47) | CSF1RMAP4K3KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL27650112 | 0.83 | CSF1R (0.45) | CSF1RMAP4K3KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5484072 | 0.82 | CSF1R (0.45) | CSF1RMET | |
| SCHEMBL488449 | 0.82 | CSF1R (0.45) | CSF1RKDM4EMET | |
| SCHEMBL30454721 | 0.82 | CSF1R (0.45) | CSF1RKDM4EMET | |
| SCHEMBL5487393 | 0.82 | CSF1R (0.48) | CSF1RKDM4ERAB9ASMN1; SMN2MET | |
| SCHEMBL488880 | 0.79 | CSF1R (0.38) | CSF1RMAP4K3KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL488418 | 0.78 | CSF1R (0.41) | CSF1RMET | |
| SCHEMBL30452632 | 0.78 | CSF1R (0.41) | CSF1RMET | |
| SCHEMBL28756897 | 0.78 | MET (0.51) | MAP4K3METJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |