Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.37 |
| ▸ | MET | P08581 | 4/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488418 | 1.00 | CSF1R (0.41) | CSF1RATRFGFR2FLT3LRRK2 | |
| SCHEMBL487614 | 0.84 | MET (0.47) | LRRK2METPIK3CADYRK1ADYRK2 | |
| SCHEMBL5484077 | 0.82 | CSF1R (0.47) | CSF1RATRMET | |
| SCHEMBL5487393 | 0.81 | CSF1R (0.48) | CSF1RATRMET | |
| SCHEMBL27629906 | 0.78 | CSF1R (0.45) | CSF1RMET | |
| SCHEMBL27650112 | 0.78 | CSF1R (0.45) | CSF1RMET | |
| SCHEMBL488920 | 0.78 | MPO (0.44) | CSF1RMET | |
| SCHEMBL30452546 | 0.78 | MPO (0.44) | CSF1RMET | |
| SCHEMBL488449 | 0.77 | CSF1R (0.45) | CSF1RATRMET | |
| SCHEMBL30454721 | 0.77 | CSF1R (0.45) | CSF1RATRMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |