Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 6/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.64 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614035 | 0.92 | HSD11B1 (0.77) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27629852 | 0.88 | ALDH1A1 (0.74) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27629846 | 0.88 | KMT2A (0.67) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27630226 | 0.87 | ALDH1A1 (0.73) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL3618130 | 0.86 | ALDH1A1 (0.72) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27629900 | 0.86 | KMT2A (0.76) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27629873 | 0.86 | KMT2A (0.79) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27630054 | 0.86 | KMT2A (0.72) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL28756762 | 0.85 | ALDH1A1 (0.70) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL27630189 | 0.85 | ALDH1A1 (0.70) | KMT2AMEN1POLBALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812784-A | New use i | BIOVITRUM AB (SE) | 2006-08-02 | — | — | CN | claimed |
| CN-1812784-A | New use i | BIOVITRUM AB (SE) | 2006-08-02 | — | — | CN | disclosed |