SCHEMBL27629945

SCHEMBL27629945

CCC(C(=O)OC1CC1)c1ncc([N+](=O)[O-])c(Cl)c1C

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
MAPT P10636 3/20 0.35
ALDH1A1 P00352 2/20 0.35
VCAM1 P19320 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
CACNA1F O60840 1/20 0.33
CACNA1D Q01668 1/20 0.33
CACNA1S Q13698 1/20 0.33
CACNA1C Q13936 1/20 0.33
CTSB P07858 1/20 0.33
RAB9A P51151 1/20 0.33
GPR174 Q9BXC1 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28756852 0.82 S1PR1 (0.35) KDM4EMAPTALDH1A1L3MBTL1CYP1A2
SCHEMBL27630131 0.72 PRKCQ (0.32)
SCHEMBL27610924 0.69 PRKCQ (0.32)
SCHEMBL6482702 0.68 MAPT (0.31) MAPT
SCHEMBL27610921 0.68 VCAM1 (0.33) ALDH1A1VCAM1
SCHEMBL20066149 0.68 MEN1 (0.39) MAPTALDH1A1L3MBTL1SMN1; SMN2KMT2A
SCHEMBL14457140 0.68 ALDH1A1 (0.38) MAPTALDH1A1L3MBTL1SMN1; SMN2KMT2A
SCHEMBL6169858 0.67 ALDH1A1 (0.34) KDM4EMAPTALDH1A1VCAM1RAB9A
SCHEMBL29923851 0.67 ALDH1A1 (0.47) MAPTALDH1A1L3MBTL1CYP1A2CYP2C19
SCHEMBL8656095 0.67 ALDH1A1 (0.47) MAPTALDH1A1L3MBTL1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1671690-A Antimicrobial azabicyclic derivatives, compositions and uses thereof PROCTER & GAMBLE (US) 2005-09-21 CN disclosed