Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629846 | 0.91 | KMT2A (0.67) | HSD11B1HSD17B1HSD17B2POLBNPC1 | |
| SCHEMBL27650156 | 0.91 | HSD11B1 (0.53) | HSD11B1HSD17B1HSD17B2POLBNPC1 | |
| SCHEMBL28756850 | 0.89 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2POLBNPC1 | |
| SCHEMBL27650025 | 0.89 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2POLBNPC1 | |
| SCHEMBL27650021 | 0.87 | HSD11B1 (0.63) | HSD11B1HSD17B1HSD17B2POLBKMT2A | |
| SCHEMBL27630180 | 0.85 | HSD11B1 (0.65) | HSD11B1HSD17B1HSD17B2POLBNPC1 | |
| SCHEMBL27650158 | 0.85 | HSD11B1 (0.60) | HSD11B1HSD17B1HSD17B2POLBKMT2A | |
| SCHEMBL27650157 | 0.83 | HSD11B1 (0.49) | HSD11B1HSD17B1HSD17B2POLBKMT2A | |
| SCHEMBL28756901 | 0.80 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2POLBKMT2A | |
| SCHEMBL3614035 | 0.79 | HSD11B1 (0.77) | HSD11B1HSD17B1HSD17B2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812784-A | New use i | BIOVITRUM AB (SE) | 2006-08-02 | — | — | CN | claimed |
| CN-1812784-A | New use i | BIOVITRUM AB (SE) | 2006-08-02 | — | — | CN | disclosed |