Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3618080 | 0.89 | HSD11B1 (0.72) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL7166097 | 0.87 | HSD11B1 (0.57) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL27650018 | 0.81 | HSD11B1 (0.43) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL27629846 | 0.81 | KMT2A (0.67) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL27630180 | 0.80 | HSD11B1 (0.65) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL27629969 | 0.80 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL27650021 | 0.79 | HSD11B1 (0.63) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL20899779 | 0.79 | HSD11B1 (0.74) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL28756850 | 0.79 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 | |
| SCHEMBL27650025 | 0.79 | HSD11B1 (0.56) | HSD11B1HSD17B1HSD17B2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812784-A | New use i | BIOVITRUM AB (SE) | 2006-08-02 | — | — | CN | claimed |
| CN-1812784-A | New use i | BIOVITRUM AB (SE) | 2006-08-02 | — | — | CN | disclosed |