Acetic Acid Methyl Ester

Acetic Acid Methyl Ester

SCHEMBL27630451

CCCC#CO.COC(C)=O

nearest known ligand 0.46

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
PTGS2 P35354 2/20 0.35
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Carbamate SCHEMBL27491385 0.84 ALOX15 (0.36) LMNAHSD17B10CA1CA2GRIK1
SCHEMBL129173 0.80
Methyl Alcohol SCHEMBL29055878 0.77
Methane SCHEMBL8910474 0.77
Charcoal, Activated SCHEMBL30358619 0.77
Acetic Acid Methyl Ester SCHEMBL17274578 0.77 ALDH1A1 (0.40) ALDH1A1PTGS2LMNAHSD17B10GRIK1
Carbamic Acid SCHEMBL28356704 0.76 GRIK1 (0.40) ALDH1A1CA1CA2GRIK1GRIK2
Acetic Acid Methyl Ester SCHEMBL27595137 0.74
Bicarbonate SCHEMBL15968046 0.72 GRIK1 (0.47) ALDH1A1GRIK1GRIK2
Bicarbonate SCHEMBL165177 0.72 GRIK1 (0.47) ALDH1A1GRIK1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1796361-A Method for synthesizing tertiary alcohol carboxylate from tertiary alcohol and carboxylic acid anhydrides LANZHOU INST OF CHEMISTRY & PH (CN) 2006-07-05 CN disclosed