Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4067456 | 0.81 | HTR6 (0.53) | HTR6 | |
| SCHEMBL27630671 | 0.76 | HTR6 (0.44) | HTR6CHRM1HRH1 | |
| SCHEMBL27611350 | 0.69 | HTR6 (0.40) | HTR6 | |
| SCHEMBL30879853 | 0.67 | HTR6 (0.47) | HTR6 | |
| SCHEMBL4074283 | 0.67 | HTR6 (0.62) | HTR6 | |
| SCHEMBL4073075 | 0.66 | HTR6 (0.83) | HTR6 | |
| SCHEMBL4816979 | 0.63 | HTR6 (0.57) | HTR6 | |
| SCHEMBL27361621 | 0.61 | CYP11B1 (0.37) | — | |
| SCHEMBL4074677 | 0.60 | HTR6 (0.60) | HTR6 | |
| SCHEMBL27746458 | 0.60 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1668590-A | 1-heterocyclylalkyl-3-sulfonyl-indole or -indazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2005-09-14 | — | — | CN | claimed |
| CN-100351236-C | 1-heterocyclylalkyl-3-sulfonyl-indole derivatives as 5-hydroxytryptamine-6 ligands, process for their preparation and their use | WYETH CORP (US) | 2007-11-28 | — | — | CN | disclosed |
| CN-1668590-A | 1-heterocyclylalkyl-3-sulfonyl-indole or -indazole derivatives as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2005-09-14 | — | — | CN | disclosed |