Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5141079 | 0.84 | PDE4A (0.40) | — | |
| SCHEMBL17018057 | 0.82 | PDE4A (0.42) | — | |
| SCHEMBL4067456 | 0.73 | HTR6 (0.53) | HTR6 | |
| SCHEMBL14635974 | 0.73 | RPS6KA5 (0.39) | HTR6 | |
| SCHEMBL14635975 | 0.73 | RPS6KA5 (0.39) | HTR6 | |
| SCHEMBL31693392 | 0.72 | EGFR (0.36) | HTR6 | |
| Hydrochloric Acid SCHEMBL31684272 | 0.72 | RPS6KA5 (0.38) | HTR6 | |
| Hydrochloric Acid SCHEMBL21903715 | 0.72 | RPS6KA5 (0.38) | HTR6 | |
| Hydrochloric Acid SCHEMBL21903713 | 0.72 | RPS6KA5 (0.38) | HTR6 | |
| SCHEMBL9832816 | 0.71 | HTR6 (0.46) | HTR6HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092222-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR D AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |