⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261001 | 0.75 | MEN1 (0.33) | — | |
| SCHEMBL14231375 | 0.71 | — | — | |
| SCHEMBL568671 | 0.71 | — | — | |
| SCHEMBL12284018 | 0.70 | SCN2A (0.51) | — | |
| SCHEMBL7957710 | 0.68 | TYMP (0.42) | — | |
| SCHEMBL4034786 | 0.67 | — | — | |
| SCHEMBL14333929 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL14334534 | 0.67 | L3MBTL1 (0.31) | — | |
| SCHEMBL14333976 | 0.67 | HIF1A (0.34) | — | |
| SCHEMBL26066796 | 0.67 | KDM5A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103214420-B | Method for preparing 2-butyl-4-chloro-5-formylimidazole | TAIZHOU VOCATIONAL & TECHNICAL COLLEGE | 2015-04-08 | — | — | CN | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-105960441-B | It is used to form the coating composition of the film with impact resistance | 关西涂料株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-106831746-A | One class Yang Dai oxadiazole indole derivativeses and preparation method and application | 陈志龙 | 2017-06-13 | — | — | CN | disclosed |
| CN-105073884-A | Curable composition | LG CHEMICAL LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-101838242-B | Method for synthesizing 2-normal-butyl-4-chloro-5-formylimidazole | UNIV ZHEJIANG TECHNOLOGY | 2015-07-15 | — | — | CN | disclosed |
| CN-103214420-B | Method for preparing 2-butyl-4-chloro-5-formylimidazole | TAIZHOU VOCATIONAL & TECHNICAL COLLEGE | 2015-04-08 | — | — | CN | disclosed |
| CN-103086979-B | Method for preparing imidazole aldehyde | JIANGSU CALE NEW MATERIALS CO., LTD. (CN) | 2014-10-22 | — | — | CN | disclosed |
| CN-101657424-B | Dual-action antihypertensive agent | THERAVANCE INC US | 2014-09-24 | — | — | CN | disclosed |
| CN-103086979-A | Method for preparing imidazole aldehyde | JIANGSU CALE NEW MATERIALS CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-101652350-B | Method for producing 2-halogenoimidazole compound | SHIKOKU CHEM | 2012-05-09 | — | — | CN | disclosed |
| EP-1871745-B1 | PREPARATION OF 2-SUBSTITUTED 4-CHLORO-5-FORMYLIMIDAZOLES BY VILSMEIER REACTION OF THE CONDENSATION PRODUCT OF GLYCINE AND AN IMIDO ESTER WITH A FORMAMIDE IN THE PRESENCE OF A TRIFLATE (TRIFLUORMETHANESULPHONATE) CATALYST | DISHMAN PHARMACEUTICALS AND CH (IN) | 2010-10-20 | — | — | EP | disclosed |
| CN-101652350-A | Make the method for 2-halo imidazolium compounds | SHIKOKU CHEM JP | 2010-02-17 | — | — | CN | disclosed |
| US-20080200690-A1 | Preparation of 2-Substituted 4-Chloro-5-Formylimidazole and 5-Formylimidazole | DISHMAN PHARMACEUTICALS AND CHEMICALS LTD (IN) | 2008-08-21 | — | — | US | disclosed |
| CN-101163680-A | Vilsmeier reaction of the condensation product of glycine and imidate with formamide in the presence of triflic acid catalyst to produce 2-substituted 4-chloro-5-formylimidazoles | DISHMAN PHARMACEUTICALS AND CH (IN) | 2008-04-16 | — | — | CN | disclosed |
| EP-1871745-A2 | PREPARATION OF 2-SUBSTITUTED 4-CHLORO-5-FORMYLIMIDAZOLES BY VILSMEIER REACTION OF THE CONDENSATION PRODUCT OF GLYCINE AND AN IMIDO ESTER WITH A FORMAMIDE IN THE PRESENCE OF A TRIFLATE (TRIFLUORMETHANESULPHONATE) CATALYST | Disham Pharmaceuticals and Chemicals Ltd. (IN) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006110037-A2 | PREPARATION OF 2-SUBSTITUTED 4-CHL0R0-5-F0RMYLIMIDAZ0LES BY VILSMEIER REACTION OF THE CONDENSATION PRODUCT OF GLYCINE AND AN IMIDO ESTER WITH A FORMAMIDE IN THE PRESENCE OF A TRIFLATE (TRIFLUORMETHANΞSULPHONATE) CATALYST | DISHMAN PHARMACEUTICALS AND CHEMICALS LTD. (IN) | 2006-10-19 | — | — | WO | disclosed |
| CN-1055361-A | Substituted pyrroles, process for their preparation, preparations containing them and their use | HOECHST AG (DE) | 1991-10-16 | — | — | CN | disclosed |