Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 8/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028599 | 1.00 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19PARP1 | |
| SCHEMBL2770161 | 0.87 | TSHR (0.42) | CYP1A2CYP3A4CYP2C9CYP2C19PARP1 | |
| SCHEMBL4248218 | 0.85 | GAA (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19PARP1 | |
| SCHEMBL8908855 | 0.81 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C9CYP2C19ACHE | |
| SCHEMBL2769605 | 0.79 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9CYP2C19PARP1 | |
| SCHEMBL2763503 | 0.71 | SERPINE1 (0.40) | CYP1A2PARP1 | |
| SCHEMBL14028600 | 0.71 | SERPINE1 (0.40) | CYP1A2PARP1 | |
| SCHEMBL13377604 | 0.71 | SERPINE1 (0.47) | CYP1A2PARP1GAA | |
| SCHEMBL13376141 | 0.71 | SERPINE1 (0.47) | CYP1A2PARP1GAA | |
| SCHEMBL14028594 | 0.71 | SERPINE1 (0.47) | CYP1A2PARP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230340297-A1 | PHOTOCURABLE COMPOSITION | KOBAYASHI & CO.,LTD. (JP) | 2023-10-26 | — | — | US | disclosed |
| EP-4238997-A1 | PHOTOCURABLE COMPOSITION | Kobayashi & Co., Ltd. (JP) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022091835-A1 | PHOTOCURABLE COMPOSITION | 株式会社コバヤシ | 2022-05-05 | — | — | WO | disclosed |
| EP-1085589-B1 | Battery separator | JAPAN VILENE CO LTD (JP) | 2015-11-04 | — | — | EP | disclosed |
| EP-1420785-B1 | SUBSTITUTED INDENO [1,2-C]ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORP (US) | 2010-04-28 | — | — | EP | disclosed |
| EP-1420785-B1 | SUBSTITUTED INDENO [1,2-C]ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORP (US) | 2010-04-28 | — | — | EP | disclosed |
| EP-2174659-A1 | Substituted indeno[1,2-c]isoquinoline derivatives and uses thereof | Inotek Pharmaceuticals Corporation (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20090227946-A1 | LUBRICIOUS COATINGS FOR MEDICAL DEVICES | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-09-10 | — | — | US | disclosed |
| US-7544381-B2 | Lubricious coatings for medical device | BOSTON SCIENTIFIC SCIMED, INC. (US) | 2009-06-09 | — | — | US | disclosed |
| EP-2033645-A1 | Isoquinoline derivatives and methods of use thereof | Inotek Pharmaceuticals Corporation (US) | 2009-03-11 | — | — | EP | disclosed |
| US-20040039009-A1 | Isoquinoline derivatives and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION | 2004-02-26 | — | — | US | disclosed |
| US-20030171392-A1 | Substituted indeno[1,2-c]isoquinoline derivatives and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION | 2003-09-11 | — | — | US | disclosed |
| US-6586137-B1 | Provided which is hardly broken by tension during the manufacture of batteries, is hardly punctured with a plate flash, and is hardly torn off with a plate edge, thereby hardly causing a short circuit. Separator can facilitate the | JAPAN VILENE COMPANY, LTD. (JP) | 2003-07-01 | — | — | US | disclosed |
| US-20030096833-A1 | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof | INOTEK PHARMACEUTICALS CORPORATION | 2003-05-22 | — | — | US | disclosed |
| WO-2003020700-A2 | SUBSTITUTED INDENO[1,2-c]ISOQUINOLINE DERIVATIVES AND METHODS OF USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2003-03-13 | — | — | WO | disclosed |
| EP-1085589-A2 | Battery separator | Japan Vilene Company, Ltd. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-5830623-A | Pattern lithography method | KABUSHIKI KAISHA TOSHIBA (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0373537-B1 | Photosensitive poly(vinyl alcohol) derivative | STATE OF JAPAN AS REPRESENTED (JP) | 1994-08-31 | — | — | EP | disclosed |
| US-5021505-A | Photosensitive poly(vinyl alcohol) derivative | DIRECTOR GENERAL OF THE AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0373537-A1 | Photosensitive poly(vinyl alcohol) derivative | THE STATE OF JAPAN, as Represented by the DIRECTOR GENERAL of the AGENCY of INDUSTRIAL SCIENCE and TECHNOLOGY (JP) | 1990-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096833-A1 | Substituted ideno[1,2-c]isoquinoline derivatives and methods of use thereof | UGT1A1, XPO1, IPO7 | CYP1A2 21/4885CYP3A4 31/4885CYP2C9 74/4885 |
| US-20030171392-A1 | Substituted indeno[1,2-c]isoquinoline derivatives and methods of use thereof | CYP1B1, UGT1A1, CYP4B1 | CYP1A2 7/4885CYP3A4 12/4885CYP2C9 41/4885 |
| US-20040039009-A1 | Isoquinoline derivatives and methods of use thereof | CYP3A7, CYP3A5, ABCG2 | CYP1A2 26/4885CYP3A4 6/4885CYP2C9 86/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.