Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732752 | 0.87 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL2762846 | 0.81 | MEN1 (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL3674393 | 0.79 | RAB9A (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL11057658 | 0.79 | MEN1 (0.63) | RAB9ANPC1MEN1KMT2ACYP2D6 | |
| SCHEMBL2925097 | 0.76 | MEN1 (0.49) | RAB9ANPC1MEN1KMT2ACYP2D6 | |
| SCHEMBL12490673 | 0.75 | NPC1 (0.61) | RAB9ANPC1POLBALDH1A1HPGD | |
| SCHEMBL1502290 | 0.75 | MEN1 (0.51) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL18765453 | 0.74 | HRH2 (0.44) | RAB9ANPC1MEN1KMT2ACYP2D6 | |
| SCHEMBL3675219 | 0.73 | KMT2A (0.52) | RAB9ANPC1MEN1KMT2ACYP2D6 | |
| SCHEMBL1502389 | 0.73 | NPC1 (0.50) | RAB9ANPC1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091938-B1 | ANTIHISTAMINIC PIPERIDINE DERIVATIVES AND INTERMEDIATES FOR THE PREPARATION THEREOF | AVENTISUB II INC (US) | 2010-10-20 | — | — | EP | disclosed |