Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057658 | 0.82 | MEN1 (0.63) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL3674393 | 0.82 | RAB9A (0.51) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL1502414 | 0.81 | LMNA (0.47) | NPC1RAB9AMEN1KMT2AHSD11B1 | |
| SCHEMBL2925097 | 0.79 | MEN1 (0.49) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL1502290 | 0.77 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL2762846 | 0.77 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL3673731 | 0.76 | MEN1 (0.47) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL3675219 | 0.76 | KMT2A (0.52) | NPC1RAB9AMEN1KMT2ACYP2D6 | |
| SCHEMBL9653084 | 0.76 | SRD5A2 (0.57) | MEN1KMT2ATP53SRD5A2 | |
| SCHEMBL12838213 | 0.76 | EPHX2 (0.49) | RAB9AMEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289867-A2 | A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof | Jubilant Organosys Limited (IN) | 2011-03-02 | — | — | EP | disclosed |
| US-6903232-B2 | Process for the preparation of a highly pure pharmaceutical intermediate, 4-(cyclopropylcarbonyl)-α, α-dimethylphenylacetic acid | AUROBINDO PHARMA LTD. (IN) | 2005-06-07 | — | — | US | disclosed |
| US-20040077900-A1 | Process for the preparation of a highly pure pharmaceutical intermediate, 4-(cyclopropylcarbonyl)-alpha, alpha-dimethylphenylacetic acid | AUROBINDO PHARMA LIMITED (IN) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077900-A1 | Process for the preparation of a highly pure pharmaceutical intermediate, 4-(cyclopropylcarbonyl)-alpha, alpha-dimethylphenylacetic acid | CMA1, HRH1, HRH2 | NPC1 2610/4885RAB9A 2186/4885MEN1 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.