Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763743 | 0.94 | MET (0.62) | METCYP3A4 | |
| SCHEMBL2803331 | 0.91 | MET (0.63) | METCYP3A4 | |
| SCHEMBL2799999 | 0.86 | MET (0.67) | METCYP3A4 | |
| SCHEMBL2764577 | 0.84 | MET (0.52) | METCYP3A4 | |
| SCHEMBL2763281 | 0.84 | MET (0.69) | METCYP3A4 | |
| SCHEMBL3406824 | 0.84 | MET (0.43) | METCYP3A4 | |
| SCHEMBL2763492 | 0.83 | MET (0.60) | METCYP3A4 | |
| SCHEMBL3405683 | 0.82 | MET (0.43) | METCYP3A4 | |
| SCHEMBL2763570 | 0.81 | MET (0.70) | METCYP3A4 | |
| SCHEMBL3724249 | 0.81 | MET (0.64) | METCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178881-A2 | NOVEL 6-TRIAZOLOPYRIDAZINESULFANYL BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND APPLICATION AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS AND NOVEL USE AS MET INHIBITORS | Sanofi-Aventis (FR) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009056692-A2 | NOVEL 6-TRIAZOLOPYRIDAZINESULFANYL BENZOTHIAZOLE AND BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND APPLICATION AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS AND NOVEL USE AS MET INHIBITORS | SANOFI-AVENTIS (FR) | 2009-05-07 | — | — | WO | disclosed |