Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483466 | 0.89 | TDP1 (0.45) | PTGDR2NR1H4EPHX2PTGER4LMNA | |
| SCHEMBL1483465 | 0.89 | TDP1 (0.45) | PTGDR2NR1H4EPHX2PTGER4LMNA | |
| SCHEMBL12755594 | 0.89 | TDP1 (0.45) | PTGDR2NR1H4EPHX2PTGER4LMNA | |
| SCHEMBL12829728 | 0.84 | AGTR1 (0.46) | NR1H4PTGER4LMNAHTTTDP1 | |
| SCHEMBL1484330 | 0.84 | AGTR1 (0.46) | NR1H4PTGER4LMNAHTTTDP1 | |
| SCHEMBL1484332 | 0.84 | AGTR1 (0.46) | NR1H4PTGER4LMNAHTTTDP1 | |
| SCHEMBL12829340 | 0.79 | LMNA (0.43) | PTGDR2LMNAHTTTDP1NPSR1 | |
| SCHEMBL12755620 | 0.79 | AGTR1 (0.46) | EGLN3LMNAHTTTDP1 | |
| SCHEMBL1483603 | 0.78 | MAPT (0.42) | NR1H4EPHX2LMNAHTTTDP1 | |
| SCHEMBL1483600 | 0.78 | MAPT (0.42) | NR1H4EPHX2LMNAHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1798739-A | 3-alkylidenehydrazino substituted heteroaryl compounds as thrombopoietin receptor activators | NISSAN CHEMICAL IND LTD (JP) | 2006-07-05 | — | — | CN | disclosed |