Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6124199 | 0.86 | MEN1 (0.43) | MEN1KMT2ACYP2C9CYP1A2TSHR | |
| SCHEMBL31290291 | 0.76 | CTSS (0.42) | MEN1KMT2ATSHRATRPOLB | |
| SCHEMBL27659658 | 0.74 | CYP2C9 (0.49) | MEN1KMT2ACYP2C9CYP1A2TSHR | |
| SCHEMBL26694710 | 0.73 | ATR (0.43) | MEN1KMT2ASMN1; SMN2ATRALDH1A1 | |
| SCHEMBL20865565 | 0.73 | ATR (0.40) | MEN1KMT2AATRPOLBCTSS | |
| SCHEMBL6124198 | 0.73 | ATR (0.36) | MEN1KMT2ATSHRSMN1; SMN2ATR | |
| SCHEMBL27827479 | 0.72 | MEN1 (0.49) | MEN1KMT2ACYP2C9CYP1A2TSHR | |
| SCHEMBL8464230 | 0.72 | KMT2A (0.53) | MEN1KMT2ACYP2C9CYP1A2TSHR | |
| SCHEMBL4247568 | 0.70 | KMT2A (0.51) | MEN1KMT2ACYP2C9CYP1A2TSHR | |
| SCHEMBL5702932 | 0.70 | MEN1 (0.54) | MEN1KMT2ACYP2C9CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1729157-A | Substituted amino phenylacetic acids, derivatives thereof, their preparation and their use as cyclooxygenase 2 (COX-2) inhibitors | NOVARTIS AG (CH) | 2006-02-01 | — | — | CN | disclosed |