Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28562202 | 0.74 | SMN1; SMN2 (0.58) | CYP2C9MEN1KMT2APOLBNPC1 | |
| SCHEMBL27633285 | 0.74 | MEN1 (0.45) | CYP2C9MEN1KMT2APOLBKDM4E | |
| SCHEMBL24983834 | 0.72 | KCNA3 (0.47) | MEN1KMT2APOLBKDM4E | |
| SCHEMBL7431588 | 0.72 | SMN1; SMN2 (0.52) | CYP2C9MEN1KMT2APOLBNPC1 | |
| SCHEMBL8706375 | 0.70 | SMN1; SMN2 (0.50) | CYP2C9MEN1KMT2APOLBNPC1 | |
| SCHEMBL5233194 | 0.69 | NPC1 (0.51) | CYP2C9MEN1KMT2APOLBNPC1 | |
| SCHEMBL12474651 | 0.69 | MGLL (0.51) | CYP2C9POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9861538 | 0.68 | POLB (0.49) | MEN1KMT2APOLBKDM4ENPC1 | |
| SCHEMBL10686084 | 0.68 | HPGD (0.52) | CYP2C9MEN1KMT2APOLBNPC1 | |
| SCHEMBL7553158 | 0.68 | CASP3 (0.54) | CYP2C9KMT2APOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863769-A | Process for preparing aminopyrrolidine derivatives and intermediate compounds | TEIJIN PHARMA LTD (JP) | 2006-11-15 | — | — | CN | disclosed |