SCHEMBL2763341

SCHEMBL2763341

CN(C(=O)c1ccc(Br)cc1N)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.50
MAPT P10636 1/20 0.46
ALDH1A1 P00352 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
MAOB P27338 2/20 0.45
KDM4E B2RXH2 2/20 0.44
GLA P06280 1/20 0.44
KMT2A Q03164 1/20 0.43
PLAU P00749 1/20 0.43
ATM Q13315 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.40
PDK2 Q15119 1/20 0.40
HTT P42858 1/20 0.40
KDM1A O60341 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27951186 0.88 MAPT (0.58) POLBMAPTALDH1A1L3MBTL1MAOB
SCHEMBL28016826 0.84 MAPT (0.49) POLBMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL27951189 0.82 POLB (0.50) POLBMAPTMAOBKDM4EKMT2A
SCHEMBL2764215 0.81 ALDH1A1 (0.55) POLBMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL27951190 0.81 POLB (0.45) POLBMAPTALDH1A1L3MBTL1MAOB
SCHEMBL16095953 0.80 ALDH1A1 (0.59) POLBMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL5260327 0.80 POLB (0.64) POLBMAPTALDH1A1MAOBKDM4E
SCHEMBL28001824 0.79 HSP90AA1 (0.57) POLBMAPTALDH1A1L3MBTL1KDM4E
SCHEMBL11686483 0.78 IDO1 (0.59) POLBMAOBKDM4EKMT2APLAU
SCHEMBL11226521 0.78 POLB (0.49) POLBMAPTALDH1A1L3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101503393-B Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO.,LTD. (JP) 2015-08-19 CN disclosed
CN-101812021-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO 2010-08-25 CN disclosed
EP-2174933-A2 Nitrogen-containing heterocycle derivative and organic electroluminescent element using the same Idemitsu Kosan Co., Ltd. (JP) 2010-04-14 EP disclosed
CN-101503393-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-08-12 CN disclosed
CN-1784388-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2006-06-07 CN disclosed