Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625290 | 0.82 | POLB (0.55) | POLBMAOBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL27951186 | 0.81 | MAPT (0.58) | POLBMAOBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL639796 | 0.78 | AKR1C4 (0.39) | POLBMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL2763341 | 0.78 | POLB (0.50) | POLBMAOBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL3457031 | 0.76 | POLB (0.64) | POLBMAOBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL10691843 | 0.73 | MAPT (0.65) | POLBALDH1A1KMT2ALMNAHTT | |
| SCHEMBL9001638 | 0.73 | POLB (0.75) | POLBMAOBL3MBTL1KDM4EKMT2A | |
| SCHEMBL5260327 | 0.73 | POLB (0.64) | POLBMAOBALDH1A1KDM4EKMT2A | |
| SCHEMBL27574758 | 0.72 | MAPT (0.50) | POLBKDM4EMAPTHSPD1HSPE1 | |
| SCHEMBL10696103 | 0.72 | LMNA (0.49) | MAOBALDH1A1L3MBTL1LMNAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363766-A | Process for the preparation of sulfur-containing N-benzyl-amino acids and esters | BOEHRINGER INGELHEIM GMBH (DE) | 1982-12-14 | — | — | US | disclosed |