Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615708 | 0.89 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL27647172 | 0.86 | KMT2A (0.50) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL23433097 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL4178872 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL21673204 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL21673464 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL29327822 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL27615707 | 0.79 | MMP8 (0.46) | ALDH1A1KMT2AMMP8TSHRCYP3A4 | |
| SCHEMBL1809268 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A | |
| SCHEMBL19105239 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100413878-C | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2008-08-27 | — | — | CN | disclosed |
| CN-100351263-C | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2007-11-28 | — | — | CN | disclosed |
| CN-1688597-A | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2005-10-26 | — | — | CN | disclosed |
| CN-1688596-A | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof | KISSEI PHARMACEUTICAL COMPANY (JP) | 2005-10-26 | — | — | CN | disclosed |