Dipyridyl

Dipyridyl

SCHEMBL27634628

c1ccc(-c2ccccn2)nc1.c1cncnc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.74
LMNA P02545 3/20 0.74
CCR1 P32246 3/20 0.74
CCR5 P51681 3/20 0.74
CCR8 P51685 3/20 0.74
CYP1A2 P05177 1/20 0.74
POLB P06746 1/20 0.74
METAP1 P53582 1/20 0.74
BLM P54132 1/20 0.74
HIF1A Q16665 1/20 0.74
DOHH Q9BU89 1/20 0.74
P4HTM Q9NXG6 1/20 0.74
NPC1 O15118 6/20 0.61
TP53 P04637 4/20 0.61
RAB9A P51151 4/20 0.61
ALOX15 P16050 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
L3MBTL1 Q9Y468 3/20 0.61
HTT P42858 2/20 0.61
TDP1 Q9NUW8 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL892382 0.86 KDM4E (0.78) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL104482 0.86 KDM4E (0.78) KDM4ELMNACCR1CCR5CCR8
Pyrimidine SCHEMBL28309592 0.86 CYP2A6 (0.64) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL5922 0.86 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.86 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3711450 0.86 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.86 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29394083 0.85 KDM4E (0.67) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3292600 0.84 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL10395611 0.83 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535410-A Triazoloquinazolinone compound and application thereof 河北农业大学 2023-08-04 CN disclosed
CN-110678537-B Bleaching using peroxyformic acid and oxygen catalysts 埃科莱布美国股份有限公司 2021-08-10 CN disclosed
CN-110678537-A Bleaching using peroxyformic acid and oxygen catalysts 埃科莱布美国股份有限公司 2020-01-10 CN disclosed
CN-107112246-A Sinterable bonding material and semiconductor device using same 汉高股份有限及两合公司 2017-08-29 CN disclosed
CN-104364361-B Improvements relating to fabric freshness 荷兰联合利华有限公司 2017-07-21 CN disclosed
CN-104364361-A Improvements relating to fabric freshness UNILEVER NV 2015-02-18 CN disclosed
CN-103174006-A Application of bipyridyl pyrimidine metal complex to low-temperature scouring and bleaching auxiliary for textiles UNIV DONGHUA 2013-06-26 CN disclosed
CN-103174006-A Application of bipyridyl pyrimidine metal complex to low-temperature scouring and bleaching auxiliary for textiles UNIV DONGHUA 2013-06-26 CN disclosed
CN-1791665-B Stable particulate composition comprising bleach catalysts CIBA SC HOLDING AG 2010-05-26 CN disclosed
CN-1711347-B Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG 2010-05-26 CN disclosed
CN-1929921-A Use of a composition comprising metal complex compounds and polyphosphonates as catalysts for oxidations CIBA SC HOLDING AG (CH) 2007-03-14 CN disclosed
CN-1929920-A Use of metal complex compounds comprising pyridine, pyrimidine or S-triazine derived ligands as catalysts for oxidations with organic peroxy acids and/or precursors of organic peroxy acids and H2O2 CIBA SC HOLDING AG (CH) 2007-03-14 CN disclosed
CN-1791665-A Stable particulate composition comprising bleach catalysts CIBA SC HOLDING AG (CH) 2006-06-21 CN disclosed
CN-1711347-A Use of metal complex compounds as oxidation catalysts CIBA SC HOLDING AG (CH) 2005-12-21 CN disclosed