Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | CCR1 | P32246 | 3/20 | 0.78 |
| ▸ | CCR5 | P51681 | 3/20 | 0.78 |
| ▸ | CCR8 | P51685 | 3/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | METAP1 | P53582 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.78 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.78 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.78 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | TP53 | P04637 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL892382 | 1.00 | KDM4E (0.78) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL27871328 | 0.97 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3292600 | 0.97 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL7904496 | 0.97 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2685509 | 0.97 | KDM4E (0.74) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL4904857 | 0.92 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL27971550 | 0.91 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Terpyridine SCHEMBL2406854 | 0.91 | KDM4E (0.82) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29907716 | 0.88 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29351528 | 0.88 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010913-B1 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS | CISBIO BIOASSAYS (FR) | 2017-12-20 | — | — | EP | disclosed |
| US-8361715-B2 | Method for suppressing a FRET signal, FRET signal suppressor agents and use in a method for multiplexing biological events | CIS BIO INTERNATIONAL (FR) | 2013-01-29 | — | — | US | disclosed |
| EP-2425249-A1 | METHOD FOR DETECTING COMPOUNDS MODULATING DIMERS OF VFT DOMAIN MEMBRANE PROTEINS | CIS Bio International (FR) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010125314-A1 | METHOD FOR DETECTING COMPOUNDS MODULATING DIMERS OF VFT DOMAIN MEMBRANE PROTEINS | CIS-BIO INTERNATIONAL (FR) | 2010-11-04 | — | — | WO | disclosed |
| US-20090162861-A1 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS | CIS BIO INTERNATIONAL (FR) | 2009-06-25 | — | — | US | disclosed |
| EP-2010913-A1 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS | CIS BIO INTERNATIONAL (FR) | 2009-01-07 | — | — | EP | disclosed |
| EP-1849003-A1 | METHOD FOR DETECTION OF INTERACTIONS BETWEEN A RECEPTOR COUPLED TO G PROTEINS (RCPG) AND ONE OF THE GALPHA OR GALPHA/GAMMA SUB-UNITS OF A G PROTEIN | CIS BIO INTERNATIONAL (FR) | 2007-10-31 | — | — | EP | disclosed |
| WO-2007116069-A1 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS | CIS BIO INTERNATIONAL (FR) | 2007-10-18 | — | — | WO | disclosed |
| US-20060205015-A1 | Method for detecting the interactions between a G protein-coupled receptor (GPCR) and one of the Galpha or Gbetagamma subunits | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-09-14 | — | — | US | disclosed |
| WO-2006085040-A1 | METHOD FOR DETECTION OF INTERACTIONS BETWEEN A RECEPTOR COUPLED TO G PROTEINS (RCPG) AND ONE OF THE GALPHA OR GALPHA/GAMMA SUB-UNITS OF A G PROTEIN | CIS BIO INTERNATIONAL (FR) | 2006-08-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090162861-A1 | METHOD FOR SUPPRESSING A FRET SIGNAL, FRET SIGNAL SUPPRESSOR AGENTS AND USE IN A METHOD FOR MULTIPLEXING BIOLOGICAL EVENTS | NFATC1, DCLRE1B, TRAF6 | KDM4E 3499/4885LMNA 2578/4885CCR1 1804/4885 |
| US-20060205015-A1 | Method for detecting the interactions between a G protein-coupled receptor (GPCR) and one of the Galpha or Gbetagamma subunits | GNAI3, GNAI1, GNB1 | KDM4E 4710/4885LMNA 3120/4885CCR1 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.