Dipyridyl

Dipyridyl

SCHEMBL892382

c1ccc(-c2ccccn2)nc1.c1ccncc1

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.78
LMNA P02545 3/20 0.78
CCR1 P32246 3/20 0.78
CCR5 P51681 3/20 0.78
CCR8 P51685 3/20 0.78
CYP1A2 P05177 1/20 0.78
POLB P06746 1/20 0.78
METAP1 P53582 1/20 0.78
BLM P54132 1/20 0.78
HIF1A Q16665 1/20 0.78
DOHH Q9BU89 1/20 0.78
P4HTM Q9NXG6 1/20 0.78
NPC1 O15118 6/20 0.64
TP53 P04637 5/20 0.64
RAB9A P51151 5/20 0.64
SMN1; SMN2 Q16637 4/20 0.64
ALOX15 P16050 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
HTT P42858 2/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dipyridyl SCHEMBL104482 1.00 KDM4E (0.78) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL27871328 0.97 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL3292600 0.97 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL7904496 0.97 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL2685509 0.97 KDM4E (0.74) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL4904857 0.92 KDM4E (0.82) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL27971550 0.91 KDM4E (0.93) KDM4ELMNACCR1CCR5CCR8
Terpyridine SCHEMBL2406854 0.91 KDM4E (0.82) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29907716 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8
Dipyridyl SCHEMBL29351528 0.88 KDM4E (1.00) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108892666-A Fluorescence immunity analysis chelating agent and preparation method thereof with the cave-shaped structure of pyridine-bipyridyl 中国科学院长春应用化学研究所 2018-11-27 CN claimed
CN-104018211-B A kind of electrochemical etching processing method of nano-precision 厦门大学 2016-08-24 CN claimed
WO-2014136115-A1 NON-SELFABSORBING LUMINESCENT SOLAR CONCENTRATOR YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-09-12 WO claimed
EP-1771440-A4 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES AMGEN INC (US) 2009-09-02 EP claimed
EP-1771440-A1 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES Amgen, Inc (US) 2007-04-11 EP claimed
WO-2006014645-A1 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES AMGEN INC. (US) 2006-02-09 WO claimed
CN-111836849-B Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2023-04-07 CN disclosed
CN-111318172-B Preparation method of polymer-modified graphene filtering membrane 中国石油化工股份有限公司 2022-01-25 CN disclosed
CN-111836849-A Process for producing fibers, films and moldings of polybenzazole polymer (P) 巴斯夫欧洲公司 2020-10-27 CN disclosed
US-10562767-B2 Liquid-organic hydrogen carrier systems based on catalytic peptide formation and hydrogenation YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2020-02-18 US disclosed
CN-105517949-B Mixed semiconductor's polymer nano granules as Polarization-Sensitive fluorescence probe 华盛顿大学商业中心 2019-11-12 CN disclosed
EP-2629889-B1 RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF YEDA RES & DEV (IL) 2019-04-03 EP disclosed
CN-109313954-A Polymer-silica hybrid PDOT and methods of use thereof 华盛顿大学 2019-02-05 CN disclosed
WO-2006014645-A1 GENERIC PROBES FOR THE DETECTION OF PHOSPHORYLATED SEQUENCES AMGEN INC. (US) 2006-02-09 WO disclosed
US-20050170442-A1 Bimolecular optical probes Life Technologies Corporation 2005-08-04 US disclosed
WO-2005026730-A2 MULTIPLEX BINDING AND ACTIVITY ASSAYS INVITROGEN CORPORATION (US) 2005-03-24 WO disclosed
US-20050064485-A1 Multiplex binding and activity assays Life Technologies Corporation 2005-03-24 US disclosed
EP-0184384-B1 SUBSTITUTED DIHYDROQUINOLONE CARBOXYLIC ACIDS, ANTI-BACTERIAL COMPOSITIONS CONTAINING THEM PFIZER INC. (US) 1989-08-02 EP disclosed
US-4797490-A Process for the preparation of 3-(2'-fluorophenyl)pyridine PFIZER INC. (US) 1989-01-10 US disclosed
EP-0184384-A1 Substituted dihydroquinolone carboxylic acids, anti-bacterial compositions containing them PFIZER INC. (US) 1986-06-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10562767-B2 Liquid-organic hydrogen carrier systems based on catalytic peptide formation and hydrogenation DDC, ADH1C, MLEC KDM4E 2373/4885LMNA 2309/4885CCR1 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.