Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28036248 | 0.81 | SMN1; SMN2 (0.55) | MAPTTSHRGRM2MEN1KMT2A | |
| SCHEMBL8782870 | 0.80 | CYP1A2 (0.57) | ALDH1A1NPC1RAB9ABACE1CYP1A2 | |
| SCHEMBL27634777 | 0.76 | DRD1 (0.50) | MAPTTSHRGRM2MEN1KMT2A | |
| SCHEMBL9514380 | 0.76 | PTGER4 (0.45) | MAPTTSHRGRM2MEN1KMT2A | |
| SCHEMBL23354195 | 0.74 | MEN1 (0.58) | MAPTTSHRGRM2MEN1KMT2A | |
| SCHEMBL29979341 | 0.74 | MEN1 (0.58) | MAPTTSHRGRM2MEN1KMT2A | |
| SCHEMBL10967204 | 0.74 | MAPT (0.50) | MAPTTSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL30739535 | 0.73 | ALDH1A1 (0.68) | MAPTTSHRKMT2AALDH1A1NPC1 | |
| SCHEMBL9061325 | 0.73 | PPARG (0.44) | MAPTTSHRGRM2MEN1KMT2A | |
| SCHEMBL9514041 | 0.73 | PTGER4 (0.46) | MAPTALDH1A1PPARGPPARARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100567242-C | Hsp90 family protein blockers | KYOWA HAKKO KOGYO KK (JP) | 2009-12-09 | — | — | CN | disclosed |
| CN-1791568-A | Hsp90 family protein inhibitors | KYOWA HAKKO KOGYO KK (JP) | 2006-06-21 | — | — | CN | disclosed |