Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 18/20 | 0.48 |
| ▸ | CNR2 | P34972 | 4/20 | 0.48 |
| ▸ | TACR2 | P21452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677625 | 0.86 | CNR1 (0.52) | CNR1CNR2TACR2 | |
| SCHEMBL4677619 | 0.86 | CNR1 (0.52) | CNR1CNR2TACR2 | |
| SCHEMBL4677622 | 0.86 | CNR1 (0.52) | CNR1CNR2TACR2 | |
| SCHEMBL4677901 | 0.86 | CNR1 (0.52) | CNR1CNR2TACR2 | |
| SCHEMBL4677897 | 0.86 | CNR1 (0.52) | CNR1CNR2TACR2 | |
| SCHEMBL27656035 | 0.85 | ACVR1 (0.53) | ACVR1CNR1CNR2TACR2 | |
| SCHEMBL28759848 | 0.80 | CNR1 (0.53) | ACVR1CNR1CNR2 | |
| SCHEMBL4680943 | 0.76 | CNR1 (0.50) | CNR1CNR2TACR2 | |
| SCHEMBL4676879 | 0.76 | CNR1 (0.50) | CNR1CNR2TACR2 | |
| SCHEMBL27634833 | 0.75 | ATR (0.42) | ACVR1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809554-A | 3-substituted 5,6-diaryl-pyrazine-2-carboxamide and -2-sulfonamide derivatives as cb1 modulators | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | claimed |
| CN-1809554-A | 3-substituted 5,6-diaryl-pyrazine-2-carboxamide and -2-sulfonamide derivatives as cb1 modulators | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |