Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.34 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7350807 | 0.82 | GRM6 (0.36) | GRM6DPP4NPC1RAB9AKDM4E | |
| SCHEMBL7140415 | 0.77 | GRM6 (0.36) | GRM6DPP4KDM4EALDH1A1MAPT | |
| SCHEMBL27755305 | 0.70 | ALDH1A1 (0.50) | CNR1CNR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1899041 | 0.69 | PRKCZ (0.70) | PRKCZGRM6ALDH1A1MAPT | |
| Ethane SCHEMBL4640067 | 0.69 | ALDH1A1 (0.49) | CNR1CNR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5454951 | 0.69 | DPP4 (0.53) | PRKCZDPP4DPP8DPP9 | |
| SCHEMBL5841080 | 0.69 | SLC7A5 (0.42) | GRM6KDM4EALDH1A1MAPT | |
| SCHEMBL29510775 | 0.69 | GRM6 (0.44) | GRM6KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30141457 | 0.69 | GRM6 (0.44) | GRM6KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6868591 | 0.69 | SMN1; SMN2 (0.43) | AURKATPX2ANO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809554-A | 3-substituted 5,6-diaryl-pyrazine-2-carboxamide and -2-sulfonamide derivatives as cb1 modulators | ASTRAZENECA AB (SE) | 2006-07-26 | — | — | CN | disclosed |