Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP51A1 | Q16850 | 5/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 5/20 | 0.35 |
| ▸ | GLI1 | P08151 | 2/20 | 0.34 |
| ▸ | GLI2 | P10070 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468286 | 0.88 | ADRB3 (0.41) | ADRB3 | |
| SCHEMBL4456601 | 0.86 | CYP4A11 (0.37) | ADRB3BACE1 | |
| SCHEMBL6244538 | 0.86 | BACE1 (0.43) | ADRB3BACE1GLI1GLI2 | |
| SCHEMBL4463459 | 0.86 | ADRB3 (0.39) | CYP51A1ADRB3BACE1 | |
| SCHEMBL4463452 | 0.86 | ADRB3 (0.39) | CYP51A1ADRB3BACE1 | |
| SCHEMBL4464277 | 0.84 | GLI1 (0.38) | CYP51A1ADRB3GLI1GLI2GRIN1 | |
| SCHEMBL4464282 | 0.84 | GLI1 (0.38) | CYP51A1ADRB3GLI1GLI2GRIN1 | |
| SCHEMBL27656299 | 0.83 | ADRB3 (0.42) | ADRB3BACE1GLI1GLI2 | |
| SCHEMBL27635239 | 0.83 | ADRB3 (0.42) | ADRB3BACE1GLI1GLI2 | |
| SCHEMBL6237642 | 0.83 | ADRB3 (0.38) | CYP51A1ADRB3BACE1GLI1GLI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1802355-A | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-07-12 | — | — | CN | disclosed |