Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 3/20 | 0.33 |
| ▸ | GLI1 | P08151 | 1/20 | 0.33 |
| ▸ | GLI2 | P10070 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12609851 | 0.85 | SSTR4 (0.43) | ADRB3BACE1ALDH1A1KMT2ALMNA | |
| SCHEMBL4478536 | 0.84 | FFAR1 (0.38) | ADRB3ALDH1A1CYP51A1GLI1GLI2 | |
| SCHEMBL4478531 | 0.84 | FFAR1 (0.38) | ADRB3ALDH1A1CYP51A1GLI1GLI2 | |
| SCHEMBL27635152 | 0.83 | CYP51A1 (0.37) | ADRB3BACE1CYP51A1GLI1GLI2 | |
| SCHEMBL4460136 | 0.83 | ADRB1 (0.42) | ADRB3BACE1ALDH1A1MEN1KMT2A | |
| SCHEMBL4460048 | 0.82 | ADRB3 (0.44) | ADRB3BACE1 | |
| SCHEMBL27635276 | 0.82 | GLI1 (0.46) | ADRB3BACE1ALDH1A1GLI1GLI2 | |
| SCHEMBL6244538 | 0.81 | BACE1 (0.43) | ADRB3BACE1GLI1GLI2ADRB2 | |
| SCHEMBL4478505 | 0.81 | ADRB3 (0.47) | ADRB3 | |
| SCHEMBL27656299 | 0.78 | ADRB3 (0.42) | ADRB3BACE1GLI1GLI2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546086-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004002939-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-08 | — | — | WO | disclosed |