Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 11/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26259377 | 0.81 | KDM4E (0.50) | ARKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL27635343 | 0.80 | AR (0.50) | ARIMPDH2IMPDH1 | |
| SCHEMBL27635228 | 0.80 | AR (0.50) | ARKDM4ELMNAIMPDH2IMPDH1 | |
| Hydrochloric Acid SCHEMBL27616212 | 0.79 | AR (0.49) | ARKDM4ELMNAIMPDH2IMPDH1 | |
| SCHEMBL27616210 | 0.79 | AR (0.49) | ARIMPDH2IMPDH1 | |
| SCHEMBL151936 | 0.78 | IMPDH2 (0.64) | ARKDM4EALDH1A1MAPTIMPDH2 | |
| SCHEMBL29489135 | 0.78 | IMPDH2 (0.64) | ARKDM4EALDH1A1MAPTIMPDH2 | |
| SCHEMBL11193357 | 0.76 | IMPDH2 (0.61) | ARKDM4EALDH1A1MAPTIMPDH2 | |
| SCHEMBL840625 | 0.75 | MAPT (0.59) | KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL27616229 | 0.74 | AR (0.44) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1688527-A | Fused benzene derivatives and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-26 | — | — | CN | disclosed |