Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855555 | 0.78 | KDM4E (0.46) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL6372092 | 0.77 | KDM4E (0.46) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL5855482 | 0.77 | CYP3A4 (0.67) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL2339494 | 0.75 | KDM4E (0.51) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL27635255 | 0.75 | AR (0.59) | MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL6484968 | 0.75 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL3088832 | 0.74 | DRD4 (0.54) | MAPTALDH1A1KDM4EGAAKMT2A | |
| SCHEMBL15479132 | 0.74 | KDM4E (0.43) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL9289876 | 0.74 | KDM4E (0.50) | MAPTALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL27744470 | 0.74 | KMT2A (0.49) | MAPTALDH1A1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-22 | — | — | US | claimed |
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | claimed |
| WO-2023046128-A1 | A CYCLIN-DEPENDENT KINASE INHIBITOR | Taizhou Eoc Pharma Co., Ltd. (CN) | 2023-03-30 | — | — | WO | disclosed |
| EP-3569606-B1 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORP (US) | 2022-01-05 | — | — | EP | disclosed |
| EP-3569606-B1 | METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF | UNIVERSAL DISPLAY CORP (US) | 2022-01-05 | — | — | EP | disclosed |
| CN-111793069-B | Method for efficiently preparing fused ring compound containing indole structural unit | 清华大学 | 2021-05-18 | — | — | CN | disclosed |
| US-10978649-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| US-10978649-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-13 | — | — | US | disclosed |
| CN-107964013-B | Antifungal agent | 詹森药业有限公司 | 2020-11-06 | — | — | CN | disclosed |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-11-05 | — | — | US | disclosed |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2020-11-05 | — | — | US | disclosed |
| US-20070190359-A1 | Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-20070190359-A1 | Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-20070190359-A1 | Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION | 2007-08-16 | — | — | US | disclosed |
| US-7202240-B2 | Antifungal 4-substituted 5,6-dihydro-4h-pyrrolo[1,2-a][1,4] benzodiazepines | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-04-10 | — | — | US | disclosed |
| US-20040266756-A1 | Antifungal 4-substituted 5,6-dihydro-4h-pyrrolo[1,2-a][1,4] benzodiazepines | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-12-30 | — | — | US | disclosed |
| EP-1392691-A1 | ANTIFUNGAL 4-SUBSTITUTED 5,6-DIHYDRO-4 u H /u -PYRROLO 1,2-A] 1,4]BENZODIAZEPINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002034752-A1 | ANTIFUNGAL 4-SUBSTITUTED 5,6-DIHYDRO-4H-PYRROLO[1,2-A][1,4]BENZODIAZEPINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-05-02 | — | — | WO | disclosed |
| CN-1205008-A | Imidazoquinazoline derivatives | KYOWA HAKKO KOGYO KK (JP) | 1999-01-13 | — | — | CN | disclosed |
| CN-1088906-A | The phenyl phenol leukotriene antagonists that replaces | LILLY CO ELI (US) | 1994-07-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10978649-B2 | Organic electroluminescent materials and devices | NR2C2, NR2E3, NCOA2 | MAPT 4645/4885ALDH1A1 2343/4885KDM4E 2578/4885 |
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | HCN2, RAC2, HCN1 | MAPT 3456/4885ALDH1A1 1225/4885KDM4E 2112/4885 |
| US-20040266756-A1 | Antifungal 4-substituted 5,6-dihydro-4h-pyrrolo[1,2-a][1,4] benzodiazepines | CYP1B1, CBR1, CYP2E1 | MAPT 2627/4885ALDH1A1 459/4885KDM4E 1317/4885 |
| US-20200350504-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | NR2C2, NR2E3, NCOA2 | MAPT 4645/4885ALDH1A1 2343/4885KDM4E 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.