Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6580197 | 0.81 | CYP1A2 (0.57) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL4434568 | 0.74 | DAO (0.52) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL644925 | 0.74 | CYP1A2 (0.49) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL11551 | 0.71 | MEN1 (0.62) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL4063446 | 0.71 | CHRM1 (0.50) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL8581152 | 0.68 | DAO (0.53) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL27278427 | 0.67 | — | — | |
| SCHEMBL31325586 | 0.67 | ALDH3A1 (0.49) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL11034330 | 0.66 | DAO (0.50) | MEN1CYP1A2KMT2ADAOPOLB | |
| SCHEMBL981536 | 0.65 | DAO (0.59) | MEN1CYP1A2KMT2ADAOPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1823062-A | Sulfonyldihydro- benzimidazolone compounds as 5-hydroxytryptamine-6 ligands | WYETH CORP (US) | 2006-08-23 | — | — | CN | disclosed |