SCHEMBL11551

SCHEMBL11551

C=CCn1c(=O)[nH]c2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.62
CYP1A2 P05177 1/20 0.62
KMT2A Q03164 1/20 0.62
LMNA P02545 4/20 0.54
HTT P42858 3/20 0.54
HPGD P15428 3/20 0.54
MAPT P10636 2/20 0.54
TSHR P16473 2/20 0.54
MAPK1 P28482 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
ALDH1A1 P00352 1/20 0.54
POLB P06746 2/20 0.50
TP53 P04637 1/20 0.50
ALOX15 P16050 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
HSD17B10 Q99714 1/20 0.50
DAO P14920 1/20 0.49
HTR7 P34969 3/20 0.47
IDO1 P14902 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14198908 0.84 CYP1A2 (0.64) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL30530480 0.83 GRIA1 (0.52) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL11049972 0.80 CYP1A2 (0.68) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL10902799 0.80 MEN1 (0.58) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL11768010 0.80 MEN1 (0.58) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL1260406 0.80 CYP1A2 (0.64) MEN1CYP1A2KMT2AHPGDTSHR
SCHEMBL5777717 0.79 MEN1 (0.57) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL5777721 0.79 MEN1 (0.57) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL30930111 0.79 CYP1A2 (0.61) MEN1CYP1A2KMT2ALMNAHTT
SCHEMBL5779204 0.79 MEN1 (0.57) MEN1CYP1A2KMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852851-B Preparation method of basalt fiber composite photovoltaic bracket material 四川中辉创达新材料科技有限公司 2025-03-25 CN claimed
CN-118876310-A Preparation process of etched PTFE multi-cavity microcatheter 仙居翊科新材料科技有限公司 2024-11-01 CN claimed
CN-118852851-A Preparation method of basalt fiber composite photovoltaic bracket material 四川中辉创达新材料科技有限公司 2024-10-29 CN claimed
EP-1435957-B1 INHIBITORS OF GSK-3 AND CRYSTAL STRUCTURES OF GSK-3BETA PROTEIN AND PROTEIN COMPLEXES VERTEX PHARMA (US) 2009-06-17 EP claimed
CN-1060837-A BENZIMIDAZOLINONE DERIVATIVES YAMANOUCHI PHARMA CO LTD (JP) 1992-05-06 CN claimed
CN-118852851-B Preparation method of basalt fiber composite photovoltaic bracket material 四川中辉创达新材料科技有限公司 2025-03-25 CN disclosed
CN-118876310-A Preparation process of etched PTFE multi-cavity microcatheter 仙居翊科新材料科技有限公司 2024-11-01 CN disclosed
CN-118852851-A Preparation method of basalt fiber composite photovoltaic bracket material 四川中辉创达新材料科技有限公司 2024-10-29 CN disclosed
US-12031150-B2 Methods, compositions and kits for increasing genome editing efficiency VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-07-09 US disclosed
US-12024525-B2 Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment AGENEBIO, INC. (US) 2024-07-02 US disclosed
US-12005127-B2 DNA-PK inhibitors VERTEX PHARMACEUTICALS INCORPORATED (US) 2024-06-11 US disclosed
CN-118103351-A Coronavirus inhibitors 共晶制药公司 2024-05-28 CN disclosed
US-5162318-A Which have pulmonary surfactant secretion promoting activity YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1992-11-10 US disclosed
EP-0454330-A1 Benzimidazolinone derivatives YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1991-10-30 EP disclosed
US-4175129-A Antiemetic 1-(benzoxazolylalkyl)-piperidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1979-11-20 US disclosed
US-4160836-A Antiemetic 1-(benzothiazolylalkyl)piperidine derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1979-07-10 US disclosed
US-4126688-A ANTIEMETIC 1-(BENZOTRIAZOLYL-ALKYL)-PIPERIDINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1978-11-21 US disclosed
US-4126687-A ANTIEMETIC, 1-(BENZIMIDAZOLYL-ALKYL)-PIPERIDINE DERIVATIVES JANSSEN PHARMACEUTICA N.V. (BE) 1978-11-21 US disclosed
US-4110333-A ANTIEMETIC INTERMEDIATES JANSSEN PHARMACEUTICA N.V. (BE) 1978-08-29 US disclosed
US-4066772-A ANTIEMETICS JANSSEN PHARMACEUTICA N.V. (BE) 1978-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12031150-B2 Methods, compositions and kits for increasing genome editing efficiency DCLRE1B, XRCC6, MRE11 MEN1 4181/4885CYP1A2 4336/4885KMT2A 1135/4885
US-12024525-B2 Benzodiazepine derivatives, compositions, and methods for treating cognitive impairment GRM5, GABRA5, GABRE MEN1 4661/4885CYP1A2 2206/4885KMT2A 2223/4885
US-12005127-B2 DNA-PK inhibitors POLK, DTYMK, DCK MEN1 3090/4885CYP1A2 2315/4885KMT2A 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.