Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | AADAC | P22760 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687159 | 0.83 | ACACB (0.52) | HRH3MAPT | |
| SCHEMBL4233654 | 0.81 | GPR119 (0.48) | EPHX2FAAHHRH3AADACCHRM3 | |
| SCHEMBL5243542 | 0.80 | SRD5A1 (0.50) | EPHX2SRD5A1CHRM3SRD5A2 | |
| SCHEMBL2763760 | 0.78 | EPHX2 (0.50) | EPHX2FAAHHRH3MAPTSMN1; SMN2 | |
| SCHEMBL2763580 | 0.76 | EPHX2 (0.50) | EPHX2FAAHSRD5A1CHRM3 | |
| SCHEMBL2763242 | 0.75 | SMN1; SMN2 (0.56) | EPHX2FAAHHRH3MAPTSMN1; SMN2 | |
| SCHEMBL19610149 | 0.75 | KMT2A (0.46) | EPHX2SRD5A1SRD5A2 | |
| SCHEMBL20455794 | 0.74 | MEN1 (0.48) | EPHX2FAAHHRH3AADACMAPT | |
| SCHEMBL16902836 | 0.74 | MEN1 (0.48) | EPHX2FAAHHRH3AADACMAPT | |
| SCHEMBL14048083 | 0.74 | HRH3 (0.63) | HRH3MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |