Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 9/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.58 |
| ▸ | PARP1 | P09874 | 5/20 | 0.58 |
| ▸ | TNKS | O95271 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.52 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900574 | 1.00 | GUSB (0.62) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL29784109 | 0.89 | GUSB (0.68) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL1461157 | 0.89 | GUSB (0.68) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL28214511 | 0.83 | GUSB (0.57) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL28135155 | 0.81 | GUSB (0.69) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL6695759 | 0.79 | TNKS2 (0.81) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL8957840 | 0.78 | NPC1 (0.78) | HPGDKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL31138463 | 0.77 | GUSB (0.81) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL296097 | 0.77 | GUSB (1.00) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL802560 | 0.77 | GUSB (0.68) | GUSBHPGDKDM4ETNKS2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-1708306-A | Quinazolinone compounds as calcilytics | NPS PHARMA INC (US) | 2005-12-14 | — | — | CN | disclosed |