Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.63 |
| ▸ | PARP1 | P09874 | 4/20 | 0.63 |
| ▸ | TNKS | O95271 | 4/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.56 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784109 | 1.00 | GUSB (0.68) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL29900574 | 0.89 | GUSB (0.62) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL27635892 | 0.89 | GUSB (0.62) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL4080197 | 0.85 | TUBB4A (0.54) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL4085165 | 0.83 | TUBB4A (0.52) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL4080440 | 0.83 | TUBB4A (0.52) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL6695759 | 0.82 | TNKS2 (0.81) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL28135155 | 0.82 | GUSB (0.69) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL2606253 | 0.81 | GUSB (0.68) | GUSBHPGDKDM4ETNKS2PARP1 | |
| SCHEMBL802560 | 0.81 | GUSB (0.68) | GUSBHPGDKDM4ETNKS2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4642309-B2 | — | — | 2011-03-02 | — | — | JP | claimed |
| JP-2003531209-A | — | — | 2003-10-21 | — | — | JP | claimed |
| EP-1278748-A2 | INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA | ICOS CORPORATION (US) | 2003-01-29 | — | — | EP | claimed |
| WO-2001081346-A2 | INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA | ICOS CORPORATION (US) | 2001-11-01 | — | — | WO | claimed |
| JP-8143586-A | — | — | None | — | — | JP | disclosed |
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |
| CN-109879820-B | Synthetic method of quinazolinone heterocyclic compound | 扬州大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-106518789-B | A method of synthesis Quinazol derivative | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106518789-A | Method for synthesis of quinazolinone derivative | 南京理工大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106478525-A | A kind of method of synthesis quinazolone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| CN-104496915-A | Synthetic method of quinazolinone aromatic compound | UNIV HUAQIAO | 2015-04-08 | — | — | CN | disclosed |
| US-8283354-B2 | Voltage gated sodium and calcium channel inhibitors | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-10-09 | — | — | US | disclosed |
| WO-2005117889-A1 | METHODS FOR TREATING AND/OR PREVENTING ABERRANT PROLIFERATION OF HEMATOPOIETIC | ICOS CORPORATION (US) | 2005-12-15 | — | — | WO | disclosed |
| EP-1438052-A1 | INHIBITORS OF HUMAN PHOSPHATIDYL−INOSITOL 3−KINASE DELTA | ICOS CORPORATION (US) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035075-A1 | INHIBITORS OF HUMAN PHOSPHATIDYL-INOSITOL 3-KINASE DELTA | ICOS CORPORATION (US) | 2003-05-01 | — | — | WO | disclosed |
| EP-0749974-B1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2001-06-27 | — | — | EP | disclosed |
| US-5798344-A | TREATING DIABETES, HYPERLIPIDEMIA | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-08-25 | — | — | US | disclosed |
| EP-0749974-A1 | PHOSPHONIC DIESTER DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-12-27 | — | — | EP | disclosed |
| JP-H08143586-A | PHOSPHONIC ACID DIESTER DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1996-06-04 | — | — | JP | disclosed |
| US-3998951-A | Substituted 2-arylquinazolines as fungicides | FMC CORPORATION (US) | 1976-12-21 | — | — | US | disclosed |