Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | GMNN | O75496 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27539162 | 0.82 | PDXK (0.42) | MAPK1MAPTLMNAMEN1KMT2A | |
| SCHEMBL27588200 | 0.82 | PDXK (0.42) | MAPK1MAPTLMNAMEN1KMT2A | |
| SCHEMBL27606029 | 0.82 | PDXK (0.42) | MAPK1MAPTLMNAMEN1KMT2A | |
| SCHEMBL4971394 | 0.77 | KDM4E (0.43) | MAPK1MAPTLMNAKMT2AGLA | |
| SCHEMBL28806636 | 0.76 | KDM4E (0.44) | MAPTLMNAMEN1BLMKMT2A | |
| SCHEMBL27756696 | 0.74 | TLR8 (0.32) | — | |
| SCHEMBL27550757 | 0.74 | PDXK (0.40) | MAPK1MAPTLMNAMEN1KMT2A | |
| SCHEMBL31542572 | 0.73 | TDP1 (0.41) | LMNAMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL29361619 | 0.69 | DGKA (0.41) | MAPTLMNATSHRALDH1A1 | |
| SCHEMBL28031310 | 0.68 | KDM4E (0.40) | MAPTLMNAMEN1BLMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100349963-C | Multi-arm polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles | NEKTAR THERAPEUTICS AL CORP (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1732212-A | Multi-branched polypeptide-poly (ethylene glycol) block copolymers as drug delivery vehicles | NEKTAR THERAPEUTICS AL CORP (US) | 2006-02-08 | — | — | CN | disclosed |