SCHEMBL27636178

SCHEMBL27636178

CCCCCCOc1nnnc(-c2ccccc2)c1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 3/20 0.50
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
ABCB1 P08183 1/20 0.39
MEN1 O00255 2/20 0.39
CYP3A4 P08684 2/20 0.39
KMT2A Q03164 2/20 0.39
NR1I2 O75469 1/20 0.39
CHRM2 P08172 1/20 0.39
ADRA2A P08913 1/20 0.39
OPRK1 P41145 1/20 0.39
HTR2B P41595 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27875105 1.00 SOAT1 (0.50) SOAT1FAAHMGLLMAPTTP53
SCHEMBL26617284 0.86 SOAT1 (0.47) SOAT1FAAHMGLLMAPTTP53
SCHEMBL1697183 0.80 SOAT1 (0.51) SOAT1FAAHGPR84MEN1CYP3A4
SCHEMBL29101366 0.79 SMN1; SMN2 (0.50) MAPTLMNAALDH1A1KMT2ACYP1A2
SCHEMBL27982523 0.78 SOAT1 (0.46) SOAT1MEN1CYP3A4KMT2ACYP1A2
SCHEMBL27827090 0.78 SOAT1 (0.44) SOAT1FAAHMGLLMAPTLMNA
SCHEMBL31099296 0.78 SOAT1 (0.45) SOAT1MEN1CYP3A4KMT2ACYP1A2
SCHEMBL27852651 0.75 LMNA (0.48) MAPTLMNAALDH1A1KDM4EPOLB
SCHEMBL899056 0.74 FAAH (0.40) FAAHMGLLTP53LMNAALDH1A1
SCHEMBL6125527 0.72 TLR4 (0.43) SOAT1MAPTLMNAMEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109223589-A Purposes of the oleogel in UV absorbent composition 巴斯夫欧洲公司 2019-01-18 CN disclosed
CN-108635244-A Use of polyglycerol-10 stearate in sunscreen formulations to increase contact angle and thereby improve water resistance 拜尔斯道夫股份有限公司 2018-10-12 CN disclosed
CN-104053427-A Cosmetic or dermatological sunscreen preparation with improved water resistance BEIERSDORF AG 2014-09-17 CN disclosed
CN-104039299-A Use of oleogels in UV absorber compositions BASF SE 2014-09-10 CN disclosed
CN-1836009-A Surface-modified zinc oxides DEGUSSA (DE) 2006-09-20 CN disclosed