Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31041845 | 1.00 | ALDH1A1 (0.48) | ALDH1A1NPSR1EGLN1VEGFAMMP2 | |
| SCHEMBL16088173 | 0.98 | ALDH1A1 (0.49) | ALDH1A1NPSR1EGLN1VEGFAMMP2 | |
| SCHEMBL9453852 | 0.93 | ALDH1A1 (0.54) | ALDH1A1NPSR1EGLN1VEGFAMMP2 | |
| SCHEMBL9453861 | 0.86 | EGLN1 (0.53) | ALDH1A1NPSR1EGLN1VEGFAMMP2 | |
| SCHEMBL11638318 | 0.80 | CNR2 (0.52) | ALDH1A1MAPTKDM4ECNR1CNR2 | |
| SCHEMBL13962027 | 0.79 | EGLN1 (0.50) | ALDH1A1NPSR1EGLN1VEGFAMMP2 | |
| SCHEMBL7260904 | 0.79 | EGLN1 (0.46) | EGLN1VEGFAMMP2MMP9MAPT | |
| SCHEMBL2645984 | 0.78 | EGLN1 (0.56) | ALDH1A1EGLN1VEGFAMMP2MMP9 | |
| SCHEMBL10461123 | 0.78 | CNR2 (0.53) | CNR1CNR2MEN1KMT2A | |
| SCHEMBL10352380 | 0.77 | ALDH1A1 (0.41) | ALDH1A1NPSR1EGLN1VEGFAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1708481-A | N-alkyl-4-methyleneamino-3-hydroxy-2-pyridones as antimicrobials | PROCTER & GAMBLE (US) | 2005-12-14 | — | — | CN | claimed |