Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499885 | 0.84 | ATM (0.58) | EPHX1MEN1KMT2ATAAR1ATM | |
| SCHEMBL27925079 | 0.84 | ATM (0.58) | EPHX1MEN1KMT2ATAAR1ATM | |
| SCHEMBL1274700 | 0.84 | ATM (0.58) | EPHX1MEN1KMT2ATAAR1ATM | |
| SCHEMBL10885963 | 0.83 | EPHX1 (0.53) | EPHX1MEN1KMT2ATAAR1ALDH1A1 | |
| SCHEMBL27711949 | 0.83 | EPHX1 (0.53) | EPHX1MEN1KMT2ATAAR1ATM | |
| SCHEMBL7882117 | 0.82 | MMP8 (0.55) | EPHX1MEN1KMT2ATAAR1ATM | |
| SCHEMBL6952367 | 0.82 | MMP8 (0.55) | EPHX1MEN1KMT2ATAAR1ATM | |
| SCHEMBL28236423 | 0.81 | GNPAT (0.45) | KMT2AATMALDH1A1THRBCYP2C9 | |
| SCHEMBL27479297 | 0.81 | ATM (0.48) | TAAR1ATMALDH1A1THRBCYP2C9 | |
| SCHEMBL10884628 | 0.81 | EPHX1 (0.58) | EPHX1MEN1KMT2ATAAR1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085323-B | Novel synthesis process of Darunavir intermediate | 重庆圣华曦药业股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| CN-110420333-A | Targeting agent antibody coupling matter and application thereof | SCRIPPS RES INSTITUTE | 2019-11-08 | — | — | CN | disclosed |
| CN-1729156-A | Amphiphilic star-like macromolecules for drug delivery | UNIV RUTGERS (US) | 2006-02-01 | — | — | CN | disclosed |