Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 14/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2764074 | 0.80 | PDK2 (0.43) | PDK2ALDH1A1TSHRTDP1PTGDR2 | |
| SCHEMBL25596084 | 0.75 | PDK2 (0.44) | PDK2OPRM1OPRD1 | |
| SCHEMBL26157447 | 0.73 | PDK2 (0.42) | PDK2CA2PTGDR2 | |
| SCHEMBL19757718 | 0.73 | PDK2 (0.60) | PDK2ALDH1A1TDP1CA1CA2 | |
| SCHEMBL16852578 | 0.73 | PDK2 (0.60) | PDK2TDP1CA1CA2CA4 | |
| SCHEMBL2763690 | 0.72 | PDK2 (0.44) | PDK2ALDH1A1TSHRTDP1CA1 | |
| SCHEMBL22237663 | 0.72 | PDK2 (0.51) | PDK2ALDH1A1OPRM1OPRD1 | |
| SCHEMBL1923391 | 0.71 | PDK2 (0.54) | PDK2ALDH1A1TDP1OPRM1OPRD1 | |
| SCHEMBL25502728 | 0.71 | PDK2 (0.41) | PDK2ALDH1A1 | |
| SCHEMBL12460624 | 0.70 | PDK2 (1.00) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723455-B2 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1656408-B1 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-20070060736-A1 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |