Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2763687 | 0.80 | PDK2 (0.54) | PDK2PTGDR2ALDH1A1TSHRTDP1 | |
| SCHEMBL2764075 | 0.75 | MEN1 (0.35) | PDK2ALDH1A1 | |
| SCHEMBL5716862 | 0.72 | PDK2 (0.37) | PDK2 | |
| SCHEMBL25596084 | 0.71 | PDK2 (0.44) | PDK2PTPRC | |
| SCHEMBL18748421 | 0.71 | PDK2 (0.36) | PDK2PTPRCALDH1A1 | |
| SCHEMBL3286383 | 0.71 | PDK2 (0.32) | PDK2 | |
| SCHEMBL26157447 | 0.70 | PDK2 (0.42) | PDK2PTGDR2PTPRC | |
| SCHEMBL1923391 | 0.68 | PDK2 (0.54) | PDK2PTPRCALDH1A1TDP1 | |
| SCHEMBL25502728 | 0.68 | PDK2 (0.41) | PDK2ALDH1A1 | |
| SCHEMBL3885909 | 0.67 | PDK2 (0.49) | PDK2PTPRCALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723455-B2 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-1656408-B1 | CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-04-14 | — | — | EP | disclosed |
| US-20070060736-A1 | Conjugated polymers containing dihydrophenanthrene units and use thereof | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |