Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTPRA | P18433 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.36 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637217 | 0.83 | CYP1A2 (0.37) | CYP1A2HIF1ACYP2C9HSD17B10TSHR | |
| SCHEMBL7179903 | 0.80 | CYP1A2 (0.48) | CYP1A2HIF1ACYP2C9HSD17B10TSHR | |
| SCHEMBL7179907 | 0.80 | CYP1A2 (0.48) | CYP1A2HIF1ACYP2C9HSD17B10TSHR | |
| SCHEMBL27618018 | 0.74 | THRB (0.39) | ALDH1A1MAPK1NPC1MEN1KMT2A | |
| SCHEMBL27618002 | 0.74 | THRB (0.41) | CYP1A2HIF1ACYP2C9HSD17B10TSHR | |
| SCHEMBL7178612 | 0.73 | CYP1A2 (0.42) | CYP1A2HIF1ACYP2C9HSD17B10TSHR | |
| SCHEMBL27947715 | 0.70 | TSHR (0.43) | CYP1A2HSD17B10TSHRALDH1A1MAPK1 | |
| SCHEMBL13609825 | 0.69 | CYP1A2 (0.43) | CYP1A2HIF1ACYP2C9HSD17B10TSHR | |
| Hydrogen Sulfide SCHEMBL28837728 | 0.69 | TSHR (0.42) | CYP1A2HSD17B10TSHRALDH1A1MAPK1 | |
| SCHEMBL15302145 | 0.68 | TYMS (0.43) | CYP1A2CYP2C9HSD17B10ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104284942-A | Stable polymerizable UV-absorbing colorant for intraocular lens | KOWA CO | 2015-01-14 | — | — | CN | disclosed |
| CN-1894620-B | Contact lens material | MENICON CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-100529842-C | Highly safe silicone-containing material for ocular lens and process for producing the same | MENICON CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-1894620-A | Contact lens material | MENICON CO LTD (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1723411-A | High-safety ophthalmic lens material containing silicone and method for producing same | MENICON CO LTD (JP) | 2006-01-18 | — | — | CN | disclosed |