Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 13/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 12/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | CASP3 | P42574 | 2/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27637217 | 0.80 | CYP1A2 (0.37) | THRBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL27529441 | 0.77 | MEN1 (0.38) | THRBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7175326 | 0.76 | THRB (0.48) | THRBMEN1KMT2ANPC1MAPT | |
| SCHEMBL8855887 | 0.76 | THRB (0.48) | THRBMEN1KMT2ANPC1MAPT | |
| SCHEMBL7175332 | 0.76 | THRB (0.48) | THRBMEN1KMT2ANPC1MAPT | |
| SCHEMBL27637218 | 0.74 | CYP1A2 (0.39) | THRBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4328157 | 0.74 | TRPA1 (0.48) | THRBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7456137 | 0.74 | TRPA1 (0.48) | THRBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8426402 | 0.74 | MEN1 (0.49) | THRBMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29264422 | 0.72 | TRPA1 (0.47) | THRBMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104284942-B | Stable artificial lens polymerism ultraviolet radiation absorption pigment | 兴和株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-104284942-A | Stable polymerizable UV-absorbing colorant for intraocular lens | KOWA CO | 2015-01-14 | — | — | CN | disclosed |
| CN-1894620-B | Contact lens material | MENICON CO LTD | 2012-09-26 | — | — | CN | disclosed |
| CN-100529842-C | Highly safe silicone-containing material for ocular lens and process for producing the same | MENICON CO LTD (JP) | 2009-08-19 | — | — | CN | disclosed |
| CN-1894620-A | Contact lens material | MENICON CO LTD (JP) | 2007-01-10 | — | — | CN | disclosed |
| CN-1723411-A | High-safety ophthalmic lens material containing silicone and method for producing same | MENICON CO LTD (JP) | 2006-01-18 | — | — | CN | disclosed |