SCHEMBL27637802

SCHEMBL27637802

O=C(O)N[C@@H](CO)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.60
MME P08473 6/20 0.47
CA2 P00918 4/20 0.43
CA1 P00915 3/20 0.43
FOLH1 Q04609 3/20 0.39
NAALAD2 Q9Y3Q0 3/20 0.39
RIMKLA Q8IXN7 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
NFKB1 P19838 1/20 0.39
PTGS2 P35354 1/20 0.39
THPO P40225 1/20 0.39
RECQL P46063 1/20 0.39
BLM P54132 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
OR51E2 Q9H255 1/20 0.39
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14050302 1.00 TGFBR1 (0.60) TGFBR1MMECA2CA1FOLH1
SCHEMBL21950137 1.00 TGFBR1 (0.60) TGFBR1MMECA2CA1FOLH1
SCHEMBL79542 0.79 MAPT (0.64) TGFBR1MMECA2CA1FOLH1
SCHEMBL79541 0.79 MAPT (0.64) TGFBR1MMECA2CA1FOLH1
SCHEMBL4812263 0.79 TGFBR1 (0.56) TGFBR1MMECA2CA1FOLH1
SCHEMBL2307007 0.79 TGFBR1 (0.68) TGFBR1MMECA2CA1FOLH1
SCHEMBL2122264 0.79 MAPT (0.64) TGFBR1MMECA2CA1FOLH1
SCHEMBL14436512 0.79 TGFBR1 (0.56) TGFBR1MMECA2CA1FOLH1
SCHEMBL1995530 0.79 TGFBR1 (0.56) TGFBR1MMECA2CA1FOLH1
SCHEMBL2793959 0.79 TGFBR1 (0.68) TGFBR1MMECA2CA1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100491345-C Process for liquid phase synthesis of N-fluorenyl-methoxy-carbonyl-N-methyl-O-tertiary butyl serine GL BIOCHEM SHANGHAI LTD (CN) 2009-05-27 CN claimed
CN-1837189-A Process for liquid phase synthesis of N-fluorenyl-methoxy-carbonyl-N-methyl-O-tertiary butyl serine GL BIOCHEM SHANGHAI LTD (CN) 2006-09-27 CN claimed
CN-117120097-A Selective drug release of internalized bioactive compound conjugates 思进公司 2023-11-24 CN disclosed
CN-117120098-A Selective drug release of internalized bioactive compound conjugates 思进公司 2023-11-24 CN disclosed
CN-113444075-A Indoline derivative, preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2021-09-28 CN disclosed
CN-107405377-A Method for disrupting exosome, exosome disruption kit, and method for separating exosome from normal cell 三井化学株式会社 2017-11-28 CN disclosed
CN-104099401-A Phospholipase A2 hydrolysis reaction reagents SHANGHAI RAINRIVER BIOTECHNOLOGY CO LTD 2014-10-15 CN disclosed
CN-1930285-B Polypeptides from Alicyclobacillus NOVOZYMES AS 2013-12-04 CN disclosed
CN-102127579-A Preparation process of mixed milk peptide UNIV NORTHEAST AGRICULTURAL 2011-07-20 CN disclosed
CN-101628842-A Alkoxycarbonyl methoxyl group used as carboxyl protecting group CHEMICAL RESISTANT COMMAND ENG 2010-01-20 CN disclosed
CN-100379718-C N alpha-Boc-N beta-Cbz-L-2,3 diaminopropionic acid derivative synthesis method UNIV WUHAN (CN) 2008-04-09 CN disclosed
CN-1930285-A Polypeptides from Alicyclobacillus NOVOZYMES AS (DK) 2007-03-14 CN disclosed
CN-1865228-A N alpha-Boc-N beta-Cbz-L-2,3 diaminopropionic acid derivative synthesis method UNIV WUHAN (CN) 2006-11-22 CN disclosed